Proteomics

Dataset Information

0

Outer membrane and Whole cell proteome Analysis of tamA, tamB and tamAB knockout mutants compared to the wildtype


ABSTRACT: The Translocation and Assembly Module (TAM), composed of TamA and TamB, facilitates the insertion of some β-barrel proteins into the OM of Escherichia coli and Klebsiella pneumoniae, and has also been implicated in lipid homeostasis. However, its role in Pseudomonas aeruginosa remains mostly uncharacterized. To investigate TAM’s function and drug target potential in P. aeruginosa, we generated both single gene knockouts and the tamAB double knockout and isolated outer membrane proteins (OMP) and whole cell lysate (WCP) and run mass spectrometry.

INSTRUMENT(S):

ORGANISM(S): Pseudomonas Aeruginosa Pa14

TISSUE(S): Cell Culture

SUBMITTER: David Boocock  

LAB HEAD: David Boocock

PROVIDER: PXD067041 | Pride | 2025-09-16

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
10_A2_WCP.wiff Wiff
10_A2_WCP.wiff.scan Wiff
11_A3_WCP.wiff Wiff
11_A3_WCP.wiff.scan Wiff
12_A4_WCP.wiff Wiff
Items per page:
1 - 5 of 99

Similar Datasets

2024-09-04 | PXD050380 | Pride
2013-01-01 | E-GEOD-41926 | biostudies-arrayexpress
2025-06-25 | PXD051792 | Pride
2014-11-06 | E-GEOD-58388 | biostudies-arrayexpress
2021-08-06 | PXD023889 | Pride
2024-02-12 | PXD043254 | Pride
2023-03-11 | PXD036178 | Pride
2016-01-08 | E-GEOD-76522 | biostudies-arrayexpress
2025-08-04 | PXD064881 | Pride
2025-05-16 | PXD063981 | Pride