Proteomics

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Dextran-based T-cell expansion nanoparticles for manufacturing CAR T cells with augmented efficacy

ABSTRACT: Click chemistry facilitates efficient antibody conjugation to NP surfaces, yet challenges persist when incubating the NPs with culturing medium. Protein corona formation in biological environments may obscure the antibodies, limiting their interactions with T cells. Hence, we conducted proteomics analysis to investigate protein corona formation on the T-Expand surface.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Tao Zheng  

LAB HEAD: Yi Sun

PROVIDER: PXD067738 | Pride | 2026-02-09

REPOSITORIES: Pride

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