Human Lower extremity arteries LC-MS
Ontology highlight
ABSTRACT: To explore potential therapeutic targets for diabetic vascular complications, we first conducted an unbiased screen at the protein level with lower extremity vessels from non-diabetic control individuals and from patients with type 2 diabetes by LC-MS/MS (liquid chromatography-tandem mass spectrometry). A total of 1093 proteins were identified by MS, of which 116 proteins were differentially expressed (false discovery rate q-value < 0.05; fold change > 1.5 or < 1/1.5) in the 3 diabetic samples (DM) compared with 3 non-diabetic controls (Non-DM), including 92 upregulated and 24 downregulated proteins.
INSTRUMENT(S):
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Endothelium Of Artery, Artery
DISEASE(S): Type 2 Diabetes Mellitus
SUBMITTER:
Shuang Zhao
LAB HEAD: zhao shuang
PROVIDER: PXD067778 | Pride | 2025-09-05
REPOSITORIES: Pride
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