Proteomics

Dataset Information

0

Human Lower extremity arteries LC-MS


ABSTRACT: To explore potential therapeutic targets for diabetic vascular complications, we first conducted an unbiased screen at the protein level with lower extremity vessels from non-diabetic control individuals and from patients with type 2 diabetes by LC-MS/MS (liquid chromatography-tandem mass spectrometry). A total of 1093 proteins were identified by MS, of which 116 proteins were differentially expressed (false discovery rate q-value < 0.05; fold change > 1.5 or < 1/1.5) in the 3 diabetic samples (DM) compared with 3 non-diabetic controls (Non-DM), including 92 upregulated and 24 downregulated proteins.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Endothelium Of Artery, Artery

DISEASE(S): Type 2 Diabetes Mellitus

SUBMITTER: Shuang Zhao  

LAB HEAD: zhao shuang

PROVIDER: PXD067778 | Pride | 2025-09-05

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
TMT6-xueguan-repeat1-95min-20200502.raw Raw
TMT6-xueguan-repeat2-95min-20200502.raw Raw
checksum.txt Txt
txt.zip Other
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