Exosomal protein Profiling in Plasma of DOCA-Salt-Induced Hypertensive and Control Mice

ABSTRACT: This study aimed to profile exosomal protein extracted from plasma of male and female mice treated with DOCA-salt (a model for hypertension) and corresponding baseline controls. The isolated exosomal proteins were sequenced using using LC-MS/MS (Orbitrap Exploris 480+FAIMS Pro). This approach may help identify molecular mechanisms related to sex-specific hypertension responses.This study aimed to profile exosomal protein extracted from plasma of male and female mice treated with DOCA-salt (a model for hypertension) and corresponding baseline controls. The isolated exosomal proteins were sequenced using using LC-MS/MS (Orbitrap Exploris 480+FAIMS Pro). This approach may help identify molecular mechanisms related to sex-specific hypertension responses.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Blood Plasma

SUBMITTER: Vahideh Tarhriz  

LAB HEAD: Vahideh Tarhriz

PROVIDER: PXD068025 | Pride | 2026-02-09

REPOSITORIES: Pride