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Proteomic evaluation and comparison of native and decellularized human saphenous vein extracellular matrices

ABSTRACT: This project presents a label-free quantitative proteomic analysis of human saphenous vein (hSV) before and after decellularization, i.e. removal of cellular material using a CHAPS-based protocol. The study evaluated extracellular matrix preservation, vascular basement membrane composition changes, and residual cellular proteins, with protein classifications performed using MatrisomeDB and Gene Ontology annotation. The data provide a reference framework for assessing the impact of decellularization on hSV grafting material and its protein composition.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Saphenous Vein

DISEASE(S): Cardiovascular System Disease

SUBMITTER: Ingrid Maria Erika Ekman Stensland

LAB HEAD: Tuula Nyman

PROVIDER: PXD068043 | Pride | 2026-03-17

REPOSITORIES: Pride

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			Action	DRS
	LC-MS_files.zip	Other
	checksum.txt	Txt
	mqpar_replicas_combined.xml	Xml
	txt_replicas_combined.zip	Other

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