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A combined omics approach to elucidate the molecular interplay behind a beneficial Arabidopsis-Caulobacter interaction

ABSTRACT: Plants rely on complex signaling networks to regulate growth and to interact with their environment, including beneficial microbes such as plant growth–promoting rhizobacteria (PGPR). Among these microbes, Caulobacter RHG1 has been shown to enhance plant growth and is recognized by Arabidopsis roots via specific receptor-like kinases (RLKs), but the molecular mechanisms underlying the plant growth-promotion effect remain largely unknown. To investigate these mechanisms, we used an integrative approach combining proteomics and phosphoproteomics to explore how RHG1 stimulates growth in Arabidopsis thaliana. Our findings suggest that RHG1 is perceived at the root-level and this, via phosphorylation-based signaling pathways, triggers early protein-based effects that are characterized by timely modulation of defense and developmental processes, which eventually lead to plant growth promotion. Understanding the mechanisms behind such beneficial plant-microbe interactions can pave the way for more effective commercialization of PGPR-based agricultural products, and our approach offers valuable insights for future research in this field.

INSTRUMENT(S):

ORGANISM(S): Arabidopsis Thaliana (mouse-ear Cress)

SUBMITTER: Sara Dufour

LAB HEAD: Sofie Goormachtig

PROVIDER: PXD068190 | Pride | 2026-04-17

REPOSITORIES: Pride

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			Action	DRS
	B004215_Bp_PSB-171-SOGOO-AmberLampens-CaulobacterArabidopsisRoots-A1.raw	Raw
	B004217_Bp_PSB-171-SOGOO-AmberLampens-CaulobacterArabidopsisRoots-A2.raw	Raw
	B004219_Bp_PSB-171-SOGOO-AmberLampens-CaulobacterArabidopsisRoots-A3.raw	Raw
	B004221_Bp_PSB-171-SOGOO-AmberLampens-CaulobacterArabidopsisRoots-A4.raw	Raw
	B004223_Bp_PSB-171-SOGOO-AmberLampens-CaulobacterArabidopsisRoots-A5.raw	Raw

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A combined omics approach to elucidate the molecular interplay behind a beneficial Arabidopsis-Caulobacter interaction

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