Proteomic selectivity of BTK-targetting probes derivatizes with thiohaloacetamide warheads

ABSTRACT: Mino cell lysates were incubated with alkyne-modified probes derived from ibrutinib, containing either acrylamide, chloro/fluoro acetamide or thiochloro/thiofluoro acetamide warheads. The reacted proteins were enriched and quantified using DIA.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): B Cell, Blood

SUBMITTER: Ronen Gabizon  

LAB HEAD: Nir London

PROVIDER: PXD069336 | Pride | 2026-09-07

REPOSITORIES: Pride