Integrating Growth Physiology and Comparative Proteomics to Decipher Sulfur Compound Disproportionation in the Deep-Sea Hydrothermal Vent Bacterium Dissulfuribacter thermophilus S69T

ABSTRACT: This study focused on a strain belonging to a genus and class (Dissulfuribacteria) of Desulfobacterota other than those on which functional studies of sulfur disproportionation have been conducted before. Dissulfuribacter thermophilus strain S69T, which was the subject of a comparative proteomic analysis, is notable for its ability to grow by disproportionation of sulfite, thiosulfate and elemental sulfur [19]. Here, we investigated the proteomic landscape of this strain during growth via thiosulfate disproportionation (S2O3D) and in the hydrogenotrophic sulfite-containing condition (hSO3), and examined the associated sulfur chemical intermediates. Using a combination of cultivation and proteomic and analytical approaches, we provide novel insights into the physiological and biochemical mechanisms involved in these sulfur metabolism pathways.

INSTRUMENT(S):

ORGANISM(S): Dissulfuribacter Thermophilus Bacteria

SUBMITTER: Céline Henry  

LAB HEAD: Henry Celine

PROVIDER: PXD069670 | Pride | 2026-08-24

REPOSITORIES: Pride