Proteomics

Dataset Information

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Exploring Proteomic Differences in PBMCs for Sex-Specific Insights into Alzheimer’s Disease


ABSTRACT: This study investigated sex-dependent proteomic alterations in peripheral blood mononuclear cells (PBMCs) from Alzheimer’s disease (AD) patients. Quantitative DIA-based proteomics revealed both shared and sex-specific pathways, including complement activation, coagulation, and metabolic processes. These findings highlight systemic immune and metabolic remodeling in AD that differ between males and females.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood

SUBMITTER: Takako Takaku  

LAB HEAD: Colin K.

PROVIDER: PXD070232 | Pride | 2026-01-14

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
2025_01_UniProt_Homo_sapiens.fasta Fasta
CombsC_20250305_04_DIA_01.mzML Mzml
CombsC_20250305_04_DIA_01.raw Raw
CombsC_20250305_04_DIA_02.mzML Mzml
CombsC_20250305_04_DIA_02.raw Raw
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