Dataset Information

Temporally graded K48 polyubiquitin targets in the female amygdala following contextual fear conditioning

ABSTRACT: Temporally graded K48 polyubiquitin targets in the female amygdala following contextual fear conditioning

INSTRUMENT(S):

ORGANISM(S): Rattus Norvegicus (rat)

TISSUE(S): Brain, Amygdala

DISEASE(S): Post-traumatic Stress Disorder

SUBMITTER: Keith Ray

LAB HEAD: Timothy J. Jarome

PROVIDER: PXD070255 | Pride | 2026-04-27

REPOSITORIES: Pride

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Dataset's files

Source:

			Action	DRS
	250822_TJ_21_01_YA7_1_2282.d.zip	Other
	250822_TJ_21_02_YA7_1_2283.d.zip	Other
	250822_TJ_22_01_BA8_1_2261.d.zip	Other
	250822_TJ_22_02_BA8_1_2262.d.zip	Other
	250822_TJ_23_01_BA1_1_2242.d.zip	Other

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Publications

Temporal- and sex-specific changes in proteasome-dependent and independent polyubiquitination in the amygdala during fear memory formation.

Brown Brieann B Preveza Natalie N Jones Gaurav G Turner Meagan M Ray W Keith WK Jarome Timothy J TJ

Learning & memory (Cold Spring Harbor, N.Y.) 20260331 4

Strong evidence has emerged over the last two decades implicating proteasome-dependent and independent protein polyubiquitination in the memory consolidation process. Recently, it was shown that multiple forms of polyubiquitination, including proteasome-dependent K48 and proteasome-independent M1 polyubiquitination, regulate fear memory formation in a sex-dependent manner in the amygdala. However, prior work focused on single time points during the postlearning period, leaving questions about wh ...[more]

PMID: 41916668

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