Proteomics

Dataset Information

0

TMEM160 Promotes Tumor Growth in Lung Adenocarcinoma and Cervical Adenocarcinoma Cell Lines


ABSTRACT: This dataset corresponds to the proteomic characterization of the TMEM160 interactome in A549 cells using co-immunoprecipitation (Co-IP) followed by data-independent acquisition mass spectrometry (DIA-MS). TMEM160 was immunoprecipitated using an anti-TMEM160 antibody, and interacting proteins were identified through LC–MS/MS analysis using a Q-Exactive HF-X system. Protein identification and quantification were performed in DIA-NN (v1.8.1) in library-free mode using the UniProt Human reference proteome.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Lung, Permanent Cell Line Cell

DISEASE(S): Lung Adenocarcinoma

SUBMITTER: ANGELINA HERRERA-QUITERIO  

LAB HEAD: Sergio Encarnación-Guevara

PROVIDER: PXD071042 | Pride | 2025-12-01

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
20230621_M_CC_10_CoIP--A549-1.raw Raw
20230621_M_CC_1_CoIP_A549-3.raw Raw
20230621_M_CC_2_CoIP_A549-2.raw Raw
20230621_M_CC_3_CoIP_A549-1.raw Raw
20230621_M_CC_8_CoIP--A549-3.raw Raw
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Publications


The Chromosome-Centric Human Proteome Project (C-HPP) is an international initiative. It aims to create a protein list expressed in human cells by each chromosomal and mitochondrial DNA to enhance our understanding of disease mechanisms, akin to the gene list generated by the Human Genome Project. Transmembrane protein 160 (TMEM160) is a member of the transmembrane proteins (TMEM) family. TMEM proteins have been implicated in cancer-related processes, including cell proliferation, migration, epi  ...[more]

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