Hormone-dependent secretome profiling of bovine oviductal epithelial organoids

ABSTRACT: This project characterizes the hormone-dependent secretome of bovine oviductal epithelial organoids. Organoids were stimulated with estradiol or progesterone to mimic follicular and luteal phases, and their secretions were analyzed by LC-MS/MS. The resulting proteomic profiles closely matched native oviductal fluid and revealed clear endocrine-specific signatures, demonstrating that organoids faithfully reproduce the molecular and secretory landscape of the bovine oviduct.

INSTRUMENT(S):

ORGANISM(S): Bos Taurus (bovine)

TISSUE(S): Oviductal Fluid, Oviduct

SUBMITTER: Sergio Navarro  

LAB HEAD: Vicente Perez-Garcia

PROVIDER: PXD071140 | Pride | 2026-06-01

REPOSITORIES: Pride