Cysteine availability tunes ubiquitin signaling via inverse stability of LRRC58 E3 ligase and its substrate CDO1

ABSTRACT: Active cullin-RING profiling and total proteome mass spectrometry were used to uncover the inverse, cysteine-dependent, releationship between the E3 LRRC58 and its substrate CDO1.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Gisele Andree  

LAB HEAD: Brenda A. Schulman

PROVIDER: PXD071631 | Pride | 2026-04-29

REPOSITORIES: Pride