Serum proteome of the Egyptian rousette bat (Rousettus aegyptiacus) reveals signatures of immunity, proteostasis, and metabolism

ABSTRACT: Bats are increasingly studied for their ability to coexist with diverse viruses of human health importance. While this focus has yielded insights into host–pathogen dynamics, baseline physiological data from healthy bats remain limited, constraining comparative and mechanistic understanding. Serum proteomics offers a direct window into circulating proteins that underpin immune regulation, cellular maintenance, and metabolism. Here, we characterize the serum proteome of healthy, captive Egyptian rousette bats (Rousettus aegyptiacus). 
Using untargeted proteomic profiling, we identified and ranked abundant proteins across major functional categories. This work provides the first-look of the Egyptian rousette bat serum proteome, providing a reference point for cross-species comparisons and future studies of bat immunity, metabolism, and longevity.

INSTRUMENT(S):

ORGANISM(S): Rousettus Aegyptiacus (egyptian Rousette) (egyptian Fruit Bat)

TISSUE(S): Blood Serum

SUBMITTER: Brooke Genovese  

LAB HEAD: Brian H.

PROVIDER: PXD072134 | Pride | 2026-06-08

REPOSITORIES: Pride