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IPMS experimetal data about antibody of btTG protein immuno the protein sample of Styela clava adult endostyle

ABSTRACT: IPMS experimetal data about antibody of btTG protein immuno the protein sample of Styela clava adult endostyle

INSTRUMENT(S):

ORGANISM(S): Styela Clava

TISSUE(S): Epithelial Cell

DISEASE(S): Disease Free

SUBMITTER: Jin Zhang

LAB HEAD: Bo Dong

PROVIDER: PXD073162 | Pride | 2026-03-23

REPOSITORIES: Pride

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Dataset's files

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			Action	DRS
	AntiBtTGRE1.raw	Raw
	AntiBtTGRE2.raw	Raw
	IgGRE1.raw	Raw
	IgGRE2.raw	Raw
	RE1Evidence.txt	Txt

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Publications

Identification of protein precursor for thyroid hormone synthesis in basal chordate ascidian Styela clava.

Zhang Jin J Yang Likun L Beinsteiner Brice B Ma Yun Y Wei Jiankai J Yu Haiyan H Laudet Vincent V Dong Bo B

Nature communications 20260207

Thyroid hormones (THs) are essential for development, growth, and metabolism in animals. Although TH synthesis is well described in vertebrates, it remains elusive in invertebrates due to the lack of identified thyroglobulin (TG) orthologs, the protein precursor for TH synthesis. Here, we identified a functional TG-like protein in ascidian Styela clava via immunoprecipitation-mass spectrometry combined with phylogenetic and expression analyses. In vitro iodination demonstrated that ScTG-like pro ...[more]

PMID: 41654703

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