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Liver proteomics data of Larimichthys crocea infected with the Pseudomonas plecoglossicida pptse6 mutant strain and wild-type strain

ABSTRACT: The large yellow croaker (Larimichthys crocea) is a vital mariculture fish species in China. Its industry is severely constrained by visceral white-nodules disease caused by Pseudomonas plecoglossicida, yet the key virulence factors and pathogenic mechanisms of this bacterium remain incompletely understood. This study investigated the role of the pptse6 gene during infection by constructing a pptse6 gene deletion mutant (Δpptse6) of P. plecoglossicida. Results demonstrated that compared to the wild-type strain (NZBD9), the Δpptse6 strain exhibited significantly attenuated virulence. Infection with the mutant resulted in higher survival rates and alleviated hepatic mitochondrial damage and metabolic disturbances (such as triglyceride accumulation and glycogen depletion) in large yellow croakers.

INSTRUMENT(S):

ORGANISM(S): Larimichthys Crocea (large Yellow Croaker) (pseudosciaena Crocea)

TISSUE(S): Hepatocyte, Liver

SUBMITTER: Huanjiao Tan

LAB HEAD: Huanjiao Tan

PROVIDER: PXD073209 | Pride | 2026-06-28

REPOSITORIES: Pride

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			Action	DRS
	132830_sp_MJ20241224098_PP20250206010.sne	Other
	P2_1_7.raw	Raw
	P2_2_8.raw	Raw
	P2_3_9.raw	Raw
	WT_1_4.raw	Raw

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