IRE1-dependent GOLIM4 expression controls protein secretion to modulate glioblastoma cell adhesion and migration.

ABSTRACT: . In the present study, we investigated if and how IRE1 could regulate the functionality of the secretory machinery in GB cells and identified GOLIM4, a Golgi-associated molecule whose expression is regulated downstream of IRE1 through the transcription of XBP1s.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Primary Cell Line Cell, Permanent Cell Line Cell

DISEASE(S): Brain Glioblastoma Multiforme

SUBMITTER: Luc Negroni  

LAB HEAD: Tony Avril

PROVIDER: PXD074925 | Pride | 2026-03-02

REPOSITORIES: Pride