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DDA and DIA analysis of calf thymus histone modifications using Prop-PIC derivatization

ABSTRACT: Comprehensive analysis of rhe histone marks from calf thymus

INSTRUMENT(S):

ORGANISM(S): Bos Taurus (bovine)

SUBMITTER: Cristina Chiva

LAB HEAD: Eduard Sabidó

PROVIDER: PXD075498 | Pride | 2026-06-15

REPOSITORIES: Pride

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			Action	DRS
	2025MZ018_CRIS_001_01_4_5ug_DDA.pdResult	Other
	2025MZ018_CRIS_001_01_4_5ug_DDA.raw	Raw
	2025MZ018_CRIS_001_01_4_5ug_DIA.raw	Raw
	2025MZ018_CRIS_002_01_4_5ug_DDA.pdResult	Other
	2025MZ018_CRIS_002_01_4_5ug_DDA.raw	Raw

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Publications

iDeepLC: Chemical Structure Information Yields Improved Retention Time Prediction of Peptides with Unseen Modifications.

Nameni Alireza A Declercq Arthur A Gabriels Ralf R Devreese Robbe R Degroeve Sven S De Maesschalck Amélie A Dhaenens Maarten M Chiva Cristina C Sabidó Eduard E Martens Lennart L Bouwmeester Robbin R

Analytical chemistry 20260608

Deep learning has notably advanced the field of liquid chromatography-mass spectrometry-based proteomics. Accurate prediction of peptide retention times significantly enhances our ability to match LC-MS data with the correct peptides and proteins, especially for data-independent acquisition data. While numerous models predict peptide LC retention times with high accuracy, few can accurately predict the retention times of chemically modified peptides, particularly those with modifications not enc ...[more]

PMID: 42253128

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