Proteomic Signatures in Cerebrospinal Fluid and Their Clinical Associations in Patients with ME/CFS

ABSTRACT: This study evaluated the cerebrospinal fluid (CSF) proteomes from 31 patients diagnosed with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). We quantified 902 proteins, each expressed in at least eleven samples, and systematically categorized clinical factors relevant to ME/CFS symptoms—including autonomic dysfunction, neuroinflammation and metabolic disturbances.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cerebrospinal Fluid

DISEASE(S): Chronic Fatigue Syndrome

SUBMITTER: Peng Li  

LAB HEAD: Jonas Bergquist

PROVIDER: PXD076216 | Pride | 2026-04-06

REPOSITORIES: Pride