Proteomics

Dataset Information

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NC in rodent ischemic optic neuropathy model

ABSTRACT: Nostoc commune (NC), an edible cyanobacterium with established antioxidant and an-ti-inflammatory activities, has emerged as a potential functional bioresource with rel-evance to ocular health. In this study, we evaluated the effects of a crude aqueous NC extract in a rodent model of anterior ischemic optic neuropathy (rAION).

INSTRUMENT(S):

ORGANISM(S): Nostoc

TISSUE(S): Whole Body

SUBMITTER: Shun-Ping Huang  

LAB HEAD: Shun-Ping Huang

PROVIDER: PXD076497 | Pride | 2026-06-08

REPOSITORIES: Pride

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20231117-B0178-1water.mzML Mzml
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NC_converted.mztab Mztab
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Publications

<i>Nostoc commune</i> Extract Attenuates Oxidative Stress and Neuroinflammation in Ischemic Optic Neuropathy Through PI3K/AKT/mTOR Signaling.

Chien Jia-Ying JY   Chan Wei-Hsun WH   Peng Mei-Ling ML   Chau Siu-Fung SF   Tsai Hsien-Yang HY   Lee Shi-Huang SH   Chen Yu-Chen YC   Cheang Wai-Man WM   Huang Shun-Ping SP  

Antioxidants (Basel, Switzerland) 20260424 5

Non-arteritic anterior ischemic optic neuropathy (NAION) is a leading cause of sudden vision loss, yet no effective therapy exists to preserve retinal ganglion cells (RGCs) after ischemic injury. <i>Nostoc commune</i> (NC), an edible cyanobacterium with established antioxidant and anti-inflammatory activities, has emerged as a potential functional bioresource with relevance to ocular health. Here, we investigated the therapeutic effects of a crude aqueous extract of NC using a rodent model of an  ...[more]

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