Clove (Syzygium aromaticum) and its bioactive constituent eugenol alleviate psoriatic inflammation by modulating the IL-36/IL-17A axis: A proteomic and mechanistic study

ABSTRACT: An imiquimod (IMQ)-induced psoriasis-like mouse model was employed to assess the therapeutic effects of orally administered clove extract and eugenol. iTRAQ-based LC–MS/MS proteomics were performed to identify molecular alterations, followed by bioinformatics analyses.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Skin

SUBMITTER: Chiao-che Chen  

LAB HEAD: Chien-Yun Hsiang

PROVIDER: PXD077433 | Pride | 2026-05-19

REPOSITORIES: Pride