Proteomics

Dataset Information

HIPK2 loss promotes TDP-43 cytoplasmic mis-localization through MAPK-pathway and is associated with TDP-43 proteinopathy in vivo

ABSTRACT: This project investigates the role of HIPK2 in regulating TDP-43 localization. This part of the study focused on: 1. Performing interactome analysis of TDP-43 in Control (Ctrli) and HIPK2-silenced (HIPK2i) SH-SY5Y cells; 2. Characterizing phosphorylation, acetylation and ubiquitination events on TDP-43 in Ctrli and HIPK2i SH-SY5Y cells.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Carolina Cane'  

LAB HEAD: Giovanna Maria Pierantoni

PROVIDER: PXD077595 | Pride | 2026-10-01

REPOSITORIES: Pride

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Dataset's files

Source:
Action DRS
IP_Ctrli_REP1.dat Other
IP_Ctrli_REP1.raw Raw
IP_Ctrli_REP2.dat Other
IP_Ctrli_REP2.raw Raw
IP_HIPK2_REP2.dat Other
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