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Multiomics Profiling of HERV Modulation and Immune Activation via RIG-I and IFNAR Pathways in Human Airway Epithelial Cells

ABSTRACT: Comprehensive multiomics analysis to investigate host cell responses upon immune system activation in human non-tumoral airway epithelial cells (BEAS-2B). Transcriptome and proteome profiling were integrated to capture global gene and protein expression changes, together with the modulation of Human Endogenous Retroviruses (HERVs), focusing on two distinct immune activation checkpoints: RIG-I and downstream IFNAR interferon receptors.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Bronchial Epithelial Cell, Cell Culture

SUBMITTER: Sante Scognamiglio

LAB HEAD: Enzo Tramontano

PROVIDER: PXD079334 | Pride | 2026-06-11

REPOSITORIES: Pride

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			Action	DRS
	20240430_AS_LC4_GF_Sante_exp2_400ng_F01.raw	Raw
	20240430_AS_LC4_GF_Sante_exp2_400ng_F02.raw	Raw
	20240430_AS_LC4_GF_Sante_exp2_400ng_F03.raw	Raw
	20240430_AS_LC4_GF_Sante_exp2_400ng_F04.raw	Raw
	20240430_AS_LC4_GF_Sante_exp2_400ng_F05.raw	Raw

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