A comprehensive proteogenomic landscape of microproteins in Trichomonas vaginalis

ABSTRACT: Microproteins encoded by small open reading frames (sORFs) have emerged as an important class of functional proteins, but their roles in protozoan parasites remain largely unexplored. This study employed a proteogenomic strategy integrating customized protein databases with LC-MS/MS to identify translated microproteins in Trichomonas vaginalis. Mass spectrometry data were searched against a customized database containing annotated proteins and predicted sORF-encoded microproteins to experimentally validate translated microproteins identified through transcriptomic analyses. This dataset supports the proteogenomic analyses presented in the associated manuscript.

INSTRUMENT(S):

ORGANISM(S): Trichomonas Vaginalis

SUBMITTER: Jhen-Wei Syu  

LAB HEAD: Petrus Tang

PROVIDER: PXD080466 | Pride | 2026-10-06

REPOSITORIES: Pride