Comparative analysis of the proteome of CD4+ T cells overexpressing or not the FOXK1 transcription factor

ABSTRACT: Foxk1 is a transcription factor described to be involved in metabolism control. To investigate its role in T cell activation, and characterize the molecular pathways modulated by FOXK1, we analyzed by quantitative mass spectrometry the proteomes of CD4+ T cells transduced with a vector containing the Foxk1 gene and overexpressing FOXK1, or control CD4+ T cells transduced with an empty vector. Cells were either non stimulated, or activated with CD3/CD28 for 24 and 48 hours. For those 6 conditions, 4 replicates were analyzed (24 raw files).

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Primary Cell, T Cell

SUBMITTER: Anne Gonzalez de Peredo  

LAB HEAD: Anne Gonzalez de Peredo

PROVIDER: PXD080837 | Pride | 2026-08-31

REPOSITORIES: Pride