Multi-region proteomics of synaptosomes and cytosolic fractions of Chrdl1 KO and WT mouse brains

ABSTRACT: This dataset contains proteomic analyses of synaptosomal and cytosolic fractions isolated from the cortex and hippocampus of adult male wild-type (WT) and Chordin-like 1 (Chrdl1) knockout (KO) mice. The study was designed to investigate how loss of Chrdl1 affects the proteomic profile of these two brain regions under physiological conditions, with a particular focus on the synaptic proteome. Isolated fractions were processed and analyzed by liquid chromatography–tandem mass spectrometry (LC-MS/MS).

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Cerebral Cortex, Hippocampus

SUBMITTER: Elena Blanco-Suarez  

LAB HEAD: Elena Blanco‑Suarez

PROVIDER: PXD082639 | Pride | 2026-08-19

REPOSITORIES: Pride