Project description:This study aims to determine the global gene expression in vancomycin resistant Enterococcus faecium (VRE) in response to a novel essential oil-vancomycin combination, and the individual components (vancomycin, carvacrol and cuminaldehyde) to help determine the mechanism of action of this antimicrobial formulation. This formulation increases the susceptibility of VRE to vancomycin and the array provides data on the synergistic mechanism of action. Five conditions (1. Control; 2. Carvacrol, 1.98 mM; 3. Cuminaldehyde, 4.20 mM; 4. Vancomycin, 0.031 mg/l; 5. Combination, 1.98 mM Carvacrol, 4.2 mM Cuminaldehyde, 0.031 mg/l vancomycin) all with 1% DMSO were tested in triplicate with a 60 minute exposure time before extraction.

2019-12-31 | E-MTAB-8072 | biostudies-arrayexpress

Project description:The first Norwegian vanD-type vancomycin resistant enterococci (VRE)

| PRJNA627463 | ENA

Enterococcus faecium strain:VRE

Project description:Enterococcus faecium strain:VRE Genome sequencing

| PRJNA589567 | ENA