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Pagrus major

ABSTRACT: Effects of soybean meal-based diet on transcriptome in red seabream

PROVIDER: PRJDB14813 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	DRR419141.fastq.gz	Fastqsanger.gz
	DRR419142.fastq.gz	Fastqsanger.gz
	DRR419143.fastq.gz	Fastqsanger.gz
	DRR419144.fastq.gz	Fastqsanger.gz
	DRR419145.fastq.gz	Fastqsanger.gz

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Project description:Single cell proteins, such as Candida utilis, are known to have immunomodulating effects in the distal intestine (DI) of Atlantic salmon, whereas soybean meal (SBM) can cause soybean meal induce enteritis (SBMIE). Inflammatory or immunomodulatory stimuli at the local level in the intestine may alter the plasma protein profile of Atlantic salmon. These changes can be helpful tools in diagnosis for fish diseases and indicators for fish health. The present work aimed to identify local intestinal tissue responses and changes in plasma protein profiles of Atlantic salmon fed C. utilis yeast, SBM, or combined diets. Fish meal (FM) based diet was used as a control diet and the six experimental diets were: FM diet with 200 g/kg C. utilis (FM200CU) and five diets containing 200 g/kg SBM together with 0 (SBM group), 25, 50, 100 or 200 g/kg C. utilis (SBM25CU, SBM50CU, SBM100CU and SBM200CU groups, respectively). Intestine morphology of fish fed FM200CU where not affected whereas SBM group presented changes characteristic of SBMIE. Low inclusion of C. utilis in SBM diet showed a modulation of immune cell populations, but did not alleviate inflammatory symptom.

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