Mus musculus strain:C57BL6/J
Ontology highlight
ABSTRACT:
PROVIDER: PRJDB15340 | ENA |
REPOSITORIES: ENA
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| DRR446105_1.fastq.gz | Fastqsanger.gz | |||
| DRR446105_2.fastq.gz | Fastqsanger.gz | |||
| DRR446106_1.fastq.gz | Fastqsanger.gz | |||
| DRR446106_2.fastq.gz | Fastqsanger.gz | |||
| DRR446107_1.fastq.gz | Fastqsanger.gz |
Items per page: 5 1 - 5 of 12 |
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Project description:Purpose: This study seeks to determine whether GLI3 is required to recruit the SMARCC1 complex to GLI enhancers in the limb. Methods: To determine if Gli3 is required to recruit SMARCC1 to its anhancers, we performed differential chromatin binding to compare SMARCC1 binding in control and Gli3 mutants. We performed Cut&Run for SMARCC1 binding on individually genotyped E11.5 (40-43s) anterior forelimb pairs from control (Gli3+/+; 3 replicates) and Gli3 mutant (Gli3-/-; 4 replicates) embryos. Results: We found that there is no major difference in SMARCC1 binding in Gli3-mutants compared to controls.
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