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Homo sapiens

ABSTRACT: Effect of GPX4 inhibitor in trophoblast BeWo cells

PROVIDER: PRJDB19861 | ENA |

REPOSITORIES: ENA

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			Action	DRS
		Other
	DRR702321_1.fastq.gz	Fastqsanger.gz
	DRR702321_2.fastq.gz	Fastqsanger.gz

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Homo sapiens Transcriptome or Gene expression

Project description:Asthma is a chronic inflammatory airway disease characterized by airway inflammation and remodeling. The role of 15-oxo-5Z,8Z,11Z,13E-eicosatetraenoic acid (15-oxoETE), a 15-HETE metabolite catalyzed by 15-prostaglandin dehydrogenase (15-PGDH), has been relatively unexplored in asthma. In this study, we used RNA-seq to explore the effect of 15-KETE on the transcriptome of airway epithelial cells, aiming to identify its potential downstream targets and mechanisms of action.

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