Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Bos taurus

ABSTRACT: Transcriptional plofile of exhausted T cells in Enzootic Bovine Leukosis

PROVIDER: PRJDB20193 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	DRR638600_1.fastq.gz	Fastqsanger.gz
	DRR638600_2.fastq.gz	Fastqsanger.gz
	DRR638601_1.fastq.gz	Fastqsanger.gz
	DRR638601_2.fastq.gz	Fastqsanger.gz
	DRR638602_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 16

Similar Datasets

Whole-transcriptome analysis of bovine leukemia virus-infected cows with contrasting proviral load levels.

Project description:Bovine leukaemia virus (BLV) is a retrovirus that infects cattle, causing Bovine Enzootic Leukosis, a chronic disease characterized by the proliferation of infected B cells. BLV proviral load (PVL) is a key determinant of disease progression and transmission risk. Cattle can exhibit distinct phenotypes of low PVL (LPVL) or high PVL (HPVL), which remain stable throughout their lifetime. Differential expression analysis performed in edgeR identified 1,908 differentially expressed genes (DEGs) between HPVL and LPVL animals, including 774 downregulated (DReg) and 1134 upregulated (UReg) genes.

2025-03-28 | GSE282244 | GEO

Bos taurus

Project description:The Transcriptional Landscape of Bovine Skeletal Muscle

| PRJNA134273 | ENA

Bos taurus

Project description:Bovine immortalized endothelial cells

| PRJDB13835 | ENA

Bos taurus

Project description:Transcriptional profiling of cumulus cells differentiation throughout oocyte competence acquisition in the bovine ovarian follicles.

| PRJNA155649 | ENA

Bos taurus

Project description:Transcriptional profiles of bovine in vivo pre-implantation development

| PRJNA254699 | ENA

Bos taurus

Project description:Bovine Glomerular and Aortic Endothelial Cells

| PRJNA84481 | ENA

Bos taurus

Project description:Bovine adult versus prepubertal cumulus cells

| PRJNA107419 | ENA

Bos taurus

Project description:Transcriptional effect of the luteinizing hormone surge in bovine granulosa cells during the peri-ovulation period

| PRJNA284959 | ENA

Diversity and evolution of 11 innate immune genes in Bos taurus taurus and Bos taurus indicus cattle.

Project description:The Toll-like receptor (TLR) and peptidoglycan recognition protein 1 (PGLYRP1) genes play key roles in the innate immune systems of mammals. While the TLRs recognize a variety of invading pathogens and induce innate immune responses, PGLYRP1 is directly microbicidal. We used custom allele-specific assays to genotype and validate 220 diallelic variants, including 54 nonsynonymous SNPs in 11 bovine innate immune genes (TLR1-TLR10, PGLYRP1) for 37 cattle breeds. Bayesian haplotype reconstructions and median joining networks revealed haplotype sharing between Bos taurus taurus and Bos taurus indicus breeds at every locus, and we were unable to differentiate between the specialized B. t. taurus beef and dairy breeds, despite an average polymorphism density of one locus per 219 bp. Ninety-nine tagSNPs and one tag insertion-deletion polymorphism were sufficient to predict 100% of the variation at all 11 innate immune loci in both subspecies and their hybrids, whereas 58 tagSNPs captured 100% of the variation at 172 loci in B. t. taurus. PolyPhen and SIFT analyses of nonsynonymous SNPs encoding amino acid replacements indicated that the majority of these substitutions were benign, but up to 31% were expected to potentially impact protein function. Several diversity-based tests provided support for strong purifying selection acting on TLR10 in B. t. taurus cattle. These results will broadly impact efforts related to bovine translational genomics.

| S-EPMC2806759 | biostudies-literature

Bos taurus

Project description:Effect of bovine viral diarrhoea virus infection in Madin-Darby bovine kidney cells

| PRJNA87705 | ENA