Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Mus musculus

ABSTRACT: RNA expression at spleen of WT and miR-142 KO mice

PROVIDER: PRJDB4295 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	DRR048399_1.fastq.gz	Fastqsanger.gz
	DRR048399_2.fastq.gz	Fastqsanger.gz
	DRR048400_1.fastq.gz	Fastqsanger.gz
	DRR048400_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 4 of 4

Similar Datasets

Mus musculus

Project description:Expression data from miR-142 WT and KO spleen and bone marrow

| PRJNA338611 | ENA

Gene profiling changes in BM Lin-Sca-1+c-Kit+ cells (LSKs) from miR-142-/- (KO), miR-142+/+ (WT), miR-142-/- BCR-ABL (BC CML) and miR-142+/+ BCR-ABL (CP CML) mice. [bulk RNA-Seq]

Project description:To gain insight into how miR-142 deficit drives a BC-like transformation, we performed RNA-seq on bone marrow (BM) Lin-Sca-1+c-Kit+ cells (LSKs) harvested from normal miR-142+/+ (wt) and miR-142−/− (miR-142 KO) mice, as well as from leukemic miR-142+/+ BCR-ABL (CP CML) and miR-142−/− BCR-ABL (BC CML) mice, two weeks after BCR-ABL induction. We then performed gene expression profiling analysis using data obtained from RNA-seq of 24 samples of LSK cells from 4 mouse strains (KO vs WT, KO CML vs CML).

2022-11-01 | GSE216794 | GEO

Mus musculus

Project description:Expression data from B6 mouse miR-142 KO and WT T cells

| PRJNA246681 | ENA

Mus musculus

Project description:Spleen response following malaria infection in WT and miR-155 KO mice.

| PRJNA287151 | ENA

Mus musculus

Project description:Expression data from B6 mouse miR-142 KO and WT dendritic cells (DCs)

| PRJNA390609 | ENA

Epression profiling of miR-142 deficient CD19+ B cells

Project description:miR-142 gene is specifically and abundantly expressed in hematopoietic cells. Mice that lack this miRNA gene develop immunodeficiency and display altered hematopoeisis. We used microarrays to detect whole transcriptome changes in miR-142 null B cells. RNA from purified WT(n=3) and miR-142 KO (n=3) CD19+ B cells was extracted and hybridized to Affymetrix GeneChips. Samples in WT and KO groups are biological replicates and were isolated in age and gender matched mice.

2015-06-15 | E-GEOD-61919 | biostudies-arrayexpress

Expression data from B6 mouse miR-142 KO and WT T cells

Project description:T cells are critical for modulating immune responses. miRNAs are small, noncoding RNAs and play a significant role in T cell responses. miR-142 is a hematopoietic specific miRNA. To explore the potential role of miR-142 in regulating T cell responses, we generated mutant mice bearing a targeted deletion of the miR-142 gene. We used microarrays to detail the global programme of gene expression underlying the profile changes between miR-142 KO and WT T cell and identified distinct classes of up-regulated genes during this process. miR-142 KO mice and WT littermates (biological triplicates) matched with age and sex were selected. T cells were purified from spleens by negative selection and processed for RNA isolation and hybridization on Affymetrix microarrays.

2014-05-13 | E-GEOD-57543 | biostudies-arrayexpress

RNA-Seq JunB WT and KO Tregs Mus musculus

Project description:To understand the mechanisms through which JunB regulates Tregs-mediated immune regulation, we examined the global gene expression profiles in the JunB WT and KO Tregs by performing RNA sequencing (RNA-seq) analysis.

2019-05-07 | GSE129060 | GEO

Expression data from B6 mouse miR-142 KO and WT dendritic cells (DCs)

Project description:DCs are critical for regulating immune responses. miRNAs are small, noncoding RNAs and play a significant role in regulating immune responses. miR-142 is a hematopoietic specific miRNA. To explore the role of miR-142 in regulating DCs’ immune responses, we generated mutant mice bearing a targeted deletion of the miR-142 gene. We used microarrays to detail the global program of gene expression underlying the profile changes between miR-142 KO and WT DCs and identified distinct classes of up-regulated or down-regulated genes in steady state or LPS stimulation during this process.

2018-05-01 | GSE100043 | GEO

Expression data from B6 mouse miR-142 KO and WT T cells

2014-05-13 | GSE57543 | GEO