Project description:Muscle invasive bladder cancer (MIBC) is one of the aggressive cancer with limited treatment options. Targeted gene expression profiling in normal and tumor samples from MIBC patients could aid in identification of potential therapeutic targets. Thus we used kinase specific panel to study their expression pattern and to identify targetable genes.
Project description:The mouse intestinal bacterial collection (miBC) represents a unique resource of cultivable bacteria isolates from mice that enables engineering of minimal gut consortia.
Project description:Mice lacking 3-hydroxy-3-methylglutaryl-coenzyme A reductase (Hmgcr) in intestinal villus and crypt epithelial cells were generated using a Villin-Cre transgene. Label free proteome profiling was measure for Wild type and KO mouse.