Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNA-seq analysis of C. elegans CPEB homolog mutants.

ABSTRACT: RNA-seq analysis of C. elegans CPEB homolog mutants.

PROVIDER: PRJEB14012 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR1413350.fastq.gz	Fastqsanger.gz
	ERR1413360.fastq.gz	Fastqsanger.gz
	ERR1413351.fastq.gz	Fastqsanger.gz
	ERR1413361.fastq.gz	Fastqsanger.gz
	ERR1413352.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 27

Similar Datasets

RNA-seq analysis of C. elegans CPEB homolog mutants.

Project description:Comparative transcriptomics study between C. elegans wild-type N2 and CPEB homolog mutants: fog-1, cpb-2, and cpb-3.

2017-08-03 | E-MTAB-4720 | biostudies-arrayexpress

Spike-in SILAC MS of C. elegans CPEB homolog mutants.

Project description:Comparative proteomic study between C. elegans wild-type N2 and CPEB homolog mutants: fog-1, cpb-2, and cpb-3.

2017-08-02 | PXD004104 | Pride

RNA-seq analysis of C. elegans mina-1 mutants

Project description:Comparative transcriptomics study between C. elegans wild-type N2 and mina-1 mutants.

2019-02-13 | E-MTAB-7389 | biostudies-arrayexpress

RNA-seq analysis of C. elegans mina-1 mutants

Project description:RNA-seq analysis of C. elegans mina-1 mutants

| PRJEB29657 | ENA

RBPL-1, the C. elegans homolog of RBBP6, promotes meiotic homolog pairing through a conserved DWNN domain

Project description:Accurate chromosome segregation during meiosis depends on precise homolog pairing, a process driven by a series of specialized proteins that link chromosomes to cytoskeletal motors and coordinate chromosome movement for homolog recognition and alignment. Here, we demonstrate that RBPL-1, the C. elegans homolog of RBBP6, is necessary for normal meiotic progression, particularly for proper homolog pairing and associated nuclear reorganization. RBPL-1 is enriched on the autosomes in early and mid- pachytene nuclei. Depletion of RBPL-1 led to reduced levels of ZIM/HIM-8 family proteins and PLK-2 kinase, two critical mediators of homolog pairing. Notably, RBPL-1's role in homolog pairing is independent of the RING finger domain, which mediates ubiquitination, and its Zn knuckle domain, which is implicated in APA/mRNA processing. Instead, we reveal that the evolutionarily conserved yet functionally enigmatic DWNN domain is essential for RBPL-1's function. Our findings uncover a previously unrecognized regulatory mechanism governing homolog pairing during meiosis.

2025-04-01 | GSE293490 | GEO

Transcriptomic Analysis of pnp-1 mutants in C. elegans

Project description:We used RNA-seq to identify gene expression changes in C. elegans pnp-1 mutants

2021-04-14 | GSE165786 | GEO

C. elegans OAC mutants metabolomics in negative polarity

Project description:negative polarity of metabolomic data of C. elegans OAC mutants

2021-10-11 | MSV000088210 | MassIVE

Transcriptomic analysis of pals-22 and pals-25 mutants in C. elegans

Project description:We used RNA-seq to identify gene expression changes in C. elegans pals-22 mutants, pals-22 pals-25 double mutants, and pals-25 mutants

2022-09-02 | GSE212552 | GEO

Transcriptomic analysis of ddi-1(icb156) mutants in C. elegans

Project description:We used RNA-seq to identify gene expression changes in C. elegans ddi-1(icb156) mutants

2023-09-30 | GSE241087 | GEO

Transcriptomic analysis of pals-25(icb98gf) mutants in C. elegans

Project description:We used RNA-seq to identify gene expression changes in C. elegans pals-25(icb98gf) mutants

2022-09-02 | GSE206756 | GEO