Project description:In this study, the composition of ES of male and female L4 stage Heligmosomoides polygyrus bakeri in the presence (cultured together) or absence (cultured alone) of the opposite sex was examined using mass spectrometry.
Project description:Genomic assembly of nematode Heligmosomoides bakeri (formerly known as Heligmosomoides polygyrus bakeri), as part of the 50 Helminth Genomes Initiative sequencing of the parasitic worms that have the greatest impact on human, agricultural and veterinary disease and cause significant global health issues particularly in the developing world, or those used as model organisms.
Project description:We report analyses of the types and amounts of microRNAs found in culture media recovered after incubating approximately 3300 H. p. bakeri adult worms for 48 hours.
Project description:Exosomes secreted by a nematode parasite transfer small RNAs to mammalian cells and regulate genes of the innate immune system [Heligmosomoides polygyrus]
Project description:In the present study we analyse the proteomic changes ocurring in murine macrophages RAW264.7 following stimulation with LPS and treatment with excretory/secretory products from Nippostrongylus brasiliensis or Heligmosomoides polygyrus.