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Improved detection of gene-microbe interactions in the mouse skin microbiota using high-resolution QTL mapping of 16S rRNA transcripts

ABSTRACT: Our hypothesis is that the host genetics controls to some extent the composition of the skin microbiota. To test this hypothesis, we first generated a fifteen generation from an advanced mouse intercross line, defined the relative abundances of skin resident bacterial taxa, both using the 16S rRNA gene copy (DNA)- and transcript (RNA) level, and performed QTL mapping on the active (RNA)- and standing (DNA) communities.

PROVIDER: PRJEB15403 | ENA |

REPOSITORIES: ENA

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