Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Neisseria lactamica Colonisation

ABSTRACT: Neisseria lactamica Colonisation

PROVIDER: PRJEB2229 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR026907_1.fastq.gz	Fastqsanger.gz
	ERR026907_2.fastq.gz	Fastqsanger.gz
	ERR026908_1.fastq.gz	Fastqsanger.gz
	ERR026908_2.fastq.gz	Fastqsanger.gz
	ERR026909_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 162

Similar Datasets

Comparative genomic hybridization of one Neisseria cinerea, two Neisseria lactamica, two Neisseria gonorrhoeae, and 48 Neisseria meningitidis isolates

Project description:Microarray comparative genome hybridization (mCGH) data was collected from one Neisseria cinerea, two Neisseria lactamica, two Neisseria gonorrhoeae, and 48 Neisseria meningitidis isolates. For N. meningitidis, these isolates are from diverse clonal complexes, invasive and carriage strains, and all major serogroups. The microarray platform represented N. meningitidis strains MC58, Z2491, and FAM18 and N. gonorrhoeae FA1090.

2007-04-04 | E-TIGR-129 | biostudies-arrayexpress

Neisseria lactamica project (Southampton)

Project description:Neisseria lactamica project (Southampton)

| PRJEB9839 | ENA

Neisseria lactamica NS19

Project description:Neisseria lactamica NS19 genome sequencing project

| PRJNA60867 | ENA

Genome-wide gene expression analysis of 16HBE14 human bronchial epithelial cells in response to Neisseria

Project description:We looked at host gene expression signatures common and specfic to occasionally pathogenic N. meningitidis and commensal N. lactamica. We hypothesise that similar host cell responses during early interactions with N. meningitidis and N. lactamica could inform common mechanisms of colonisation of commensals while differential host cell responses could be capable of altering the outcome of the colonisation process. Total RNA obtained from 16HBE14 cells infected with the different strains of Neisseria from 0 to 7 hours are compared to mock-infected controls at the respective timepoints. 192 samples are analysed. There are 4 to 8 biological replicates per condition.

2012-05-31 | E-GEOD-27557 | biostudies-arrayexpress

Neisseria lactamica Y92-1009

Project description:Neisseria lactamica Y92-1009 genome sequencing project.

| PRJEA50739 | ENA

Neisseria lactamica Y92-1009

Project description:Neisseria lactamica Y92-1009 Genome sequencing and assembly

| PRJNA331097 | ENA

Neisseria lactamica ATCC 23970

Project description:Neisseria lactamica ATCC 23970 Genome sequencing and assembly

| PRJNA244570 | ENA

Genome-wide gene expression analysis of 16HBE14 human bronchial epithelial cells in response to Neisseria

2012-06-01 | GSE27557 | GEO

Microevolution of Neisseria lactamica during nasopharyngeal colonisation induced by controlled human infection.

Project description:Neisseria lactamica is a harmless coloniser of the infant respiratory tract, and has a mutually-excluding relationship with the pathogen Neisseria meningitidis. Here we report controlled human infection with genomically-defined N. lactamica and subsequent bacterial microevolution during 26 weeks of colonisation. We find that most mutations that occur during nasopharyngeal carriage are transient indels within repetitive tracts of putative phase-variable loci associated with host-microbe interactions (pgl and lgt) and iron acquisition (fetA promotor and hpuA). Recurrent polymorphisms occurred in genes associated with energy metabolism (nuoN, rssA) and the CRISPR-associated cas1. A gene encoding a large hypothetical protein was often mutated in 27% of the subjects. In volunteers who were naturally co-colonised with meningococci, recombination altered allelic identity in N. lactamica to resemble meningococcal alleles, including loci associated with metabolism, outer membrane proteins and immune response activators. Our results suggest that phase variable genes are often mutated during carriage-associated microevolution.

| S-EPMC6232127 | biostudies-literature

Neisseria lactamica 020-06

Project description:Nonpathogenic Neisseria

| PRJNA13472 | ENA