Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Mosquito Microbiome MU

ABSTRACT: Larvicidal treatment impacts the internal microbiome of mosquitoes in hurricane created larval habitat

PROVIDER: PRJEB22597 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR2122280_1.fastq.gz	Fastqsanger.gz
	ERR2122280_2.fastq.gz	Fastqsanger.gz
	ERR2122290_1.fastq.gz	Fastqsanger.gz
	ERR2122290_2.fastq.gz	Fastqsanger.gz
	ERR2122300_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 80

Similar Datasets

Eggs of the mosquito Aedes aegypti survive desiccation by rewiring their polyamine and lipid metabolism

Project description:Upon water loss, some organisms pause their life cycles and escape death. While widespread in microbes, this is less common in animals. Aedes mosquitoes are vectors for viral diseases. Aedes eggs can survive dry environments, but molecular and cellular principles enabling egg survival through desiccation remain unknown. In this report, we find that Aedes aegypti eggs, in contrast to Anopheles stephensi, survive desiccation by acquiring desiccation tolerance at a late developmental stage. We uncover unique proteome and metabolic state changes in Aedes embryos during desiccation that reflect reduced central carbon metabolism, rewiring towards polyamine production, and enhanced lipid utilization for energy and polyamine synthesis. Using inhibitors targeting these processes in blood-fed mosquitoes that lay eggs, we infer a two-step process of desiccation tolerance in Aedes eggs. The metabolic rewiring towards lipid breakdown and dependent polyamine accumulation confers resistance to desiccation. Furthermore, rapid lipid breakdown is required to fuel energetic requirements upon water re-entry to enable larval hatching and survival upon rehydration. This study is fundamental to understanding Aedes embryo survival and in controlling the spread of these mosquitoes.

2023-09-26 | PXD044525 | Pride

Mosquito

Project description:Mosquitoes gut fungal microbiome Raw sequence reads

| PRJNA1062148 | ENA

Mosquito gene expression over time

Project description:A profile of gene expression of mosquitoes

2021-03-03 | E-MTAB-10110 | biostudies-arrayexpress

Signaling between mammalian adiponectin and a mosquito adiponectin receptor reduces Plasmodium transmission

Project description:In this study we determine the effects of silencing adiponectin receptor in A. gambiae mosquitoes after taking Plasmodium gambiae infected blood meals. dsRNA (dsAdpR and dsGluc) microinjected A. gambiae mosquitoes were fed on P. berghei-infected Swiss Webster mice. Two days after a blood meal, the mosquitoes were collected for midgut dissection.

2023-11-09 | GSE198929 | GEO

mosquito metagenome

Project description:Evolution of bacteria in anopheles mosquitoes

| PRJNA272632 | ENA

Mouse skin samples after Zika virus-infected mosquito bites

Project description:Mouse skin bitten by Zika virus-infected mosquitoes were isolated and performed RNA-seq

2019-03-10 | GSE125194 | GEO

mosquito metagenome

Project description:Viral metagenome from mixed species of mosquitoes

| PRJNA28469 | ENA

mosquito metagenome

Project description:Viral metagenome from mixed species of mosquitoes

| PRJNA28467 | ENA

Activation of mosquito immunity blocks the development of transmission-stage filarial nematodes

Project description:Mosquito-borne helminth infections are responsible for a significant worldwide disease burden in both humans and animals. Accordingly, development of novel strategies to reduce disease transmission by targeting these pathogens in the vector are of paramount importance. We found that a strain of Aedes aegypti that is refractory to infection by Dirofilaria immitis, the agent of canine heartworm disease, mounts a stronger immune response during infection than does a susceptible strain. Moreover, activation of the Toll immune signaling pathway in the susceptible strain arrests larval development of the parasite, thereby decreasing the number of transmissionstage larvae. Notably, this strategy also blocks transmission stage Brugia malayi, an agent of human lymphatic filariasis. Our data show that mosquito immunity can play a pivotal role in restricting filarial nematode development and suggest that genetically engineering mosquitoes with enhanced immunity will help reduce disease transmission.

2020-02-01 | GSE142155 | GEO

mosquito metagenome

Project description:Viral metagenome isolated from mixed species of mosquitoes

| PRJNA28413 | ENA