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IBI - Wesmaelius nervosus

ABSTRACT: Wesmaelius (Kimninsia) nervosus (Fabricius, 1793) (Neuroptera, Hemerobiidae) a new species of brown lacewing for the Portuguese fauna

PROVIDER: PRJEB39608 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	ERR4383753.fastq.gz	Fastqsanger.gz
	ERR4383754.fastq.gz	Fastqsanger.gz

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Project description:Genome skimming of the Little Pansy butterfly Junonia sophia (Fabricius, 1793) (Insecta: Lepidoptera: Nymphalidae)

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Comparative proteomic analysis revealed the differential responses to novel duck reovirus infection in the bursa of Fabricius of Cairna moschata

Project description:Duck reovirus (DRV) is well-studied aquatic bird virus belonging to the Orthoreovirus genus of the Reoviridae family. The bursa of Fabricius is an immunologically organ against virus invasion. However, the responses of the bursa of Fabricius of Cairna moschata to DRV infection are largely unknown. To investigate the immune responses, the proteomes from the control and two DRV strain infected samples (NH and DJ) were compared. In total, 7075 protein were identified, of which 5625 protein were quantified. A number of differentially expressed proteins (DEPs), including 210 DEPs under the HN10 infection and 55 DEPs under the JD10 infection, were identified. Protein network analysis showed that the DEPs enriched in the serine protease system and the innate immune response clusters. For the serine protease systems, coagulation factor IX, three chains of fibrinogen, and complement C8, C5, and C2s were significantly up-regulated, suggesting that the serine protease-mediated immune might be involved in the responses to the HN10 infection. For the innate and adaptive immune system, RIG-I, MDA5, MAPK20, and IRF3 were significantly up-regulated, indicating their important role in the reorganization of invaded virus. Furthermore, the DEPs among different visceral organs (liver, spleen, and the bursa of Fabricius) were compared. coagulation factor IX was significantly up-regulated in the bursa of fabricius, not in the liver and spleen samples, suggesting an important role of the bursa of fabricius in antivirus. Our data may give a comprehensive resource for investigating the regulation mechanism involved in the responses of the bursa of Fabricius of duck to the DRV infections.

2022-08-12 | PXD025093 | Pride

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