Project description:we compared the skin transcriptomes of the black- and white-coated region from the Boer and Macheng Black crossbred goat with black head and white body using the Illumina RNA-Seq method. Six cDNA libraries derived from skin samples of the white coat region (n = 3) and black coat region (n = 3) were constructed from three full-sib goats. On average, we obtained approximately 76.5 and 73.5 million reads for each skin sample of black coat and white coat, respectively, of which 75.39% and 76.05% reads were covered in the genome database. Our study provides insight into the transcriptional regulation of two distinct coat color that might serve as a key resource for understanding coat color pigmentation of goat.
Project description:The coat color of mammals is determined by the melanogenesis pathway, which is responsible for maintaining the balance between black-brown eumelanin and yellow-reddish phaeomelanin. It is also believed that the color of the bovine nose is regulated in a similar manner; however, the molecular mechanism underlying pigment deposition in the black nose has yet to be elucidated. The aim of the present study was to identify melanogenesis-associated genes that are differentially expressed in the black vs. yellow nose of native Korean cows.
2013-12-26 | GSE53657 | GEO
Project description:A Novel TYRP1 Mutation Associated with Brown Coat Color in Siberian Huskies
Project description:Reptiles exhibit a broad variety of adaptive colours and colours patterns but little is known of the mechanisms responsible for these traits. We focus here on the Hypomelanistic traits of 1 corn snake color morph and 3 leopard gecko color morphs. We use mapping-by-sequencing and and differential expression analysis to identify the causative mutation and identify the genes involved in the phenotypes of these color morphs.
Project description:Reptiles exhibit a broad variety of adaptive colours and colours patterns but little is known of the mechanisms responsible for these traits. We focus here on the Hypomelanistic traits of 1 corn snake color morph and 3 leopard gecko color morphs. We use mapping-by-sequencing and and differential expression analysis to identify the causative mutation and identify the genes involved in the phenotypes of these color morphs.
