Project description:This SuperSeries is composed of the following subset Series: GSE35186: Paradigm Test Set Expression Array GSE35189: Paradigm Test Set aCGH Array Refer to individual Series
Project description:<p>Blood metabolomics of 12-week-old female and male C57BL/6J mice that were exposed to either a control or an unhealthy high-fat/high-sugar (HFHS) diet during early-life, or early-life HFHS diet supplemented with a microbiota-targeted intervention (either a prebiotic combination (fructo-oligosaccharides and galacto-oligosaccharides), FOS+GOS) or a putative probiotic (<em>B. longum</em> APC1472)). The overall aim of the project is to investigate the potential of microbiota-targeted approaches, via prebiotic combination FOS+GOS or the putative probiotic <em>B. longum</em> APC147, to attenuate detrimental enduring effects of an early-life HFHS diet, as a model of western diet, on offspring’s feeding behavior in adulthood.</p>