Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ESBL-sharing

ABSTRACT: Healthy companion animals and owners colonisation and sharing of ESBL/AmpC-producing Enterobacterales, Portugal and United Kingdom

PROVIDER: PRJEB51686 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR9355100_1.fastq.gz	Fastqsanger.gz
	ERR9355100_2.fastq.gz	Fastqsanger.gz
	ERR9355101_1.fastq.gz	Fastqsanger.gz
	ERR9355101_2.fastq.gz	Fastqsanger.gz
	ERR9355102_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 18

Similar Datasets

Clostridioides difficile

Project description:Clostridioides difficile from Companion Animals and Owners

| PRJNA821670 | ENA

Molecular Epidemiology of Enterobacterales Resistant to Antibiotics of Last Resort in Pregnant Women in Labour at a Tertiary Hospital

Project description:This study aims to determine the epidemiology of Enterobacteriaceae resistant to antibiotics of last resort in pregnant women in labour at a tertiary hospital, Pretoria, South Africa. Rectal swabs shall be used to screen for colonisation with CRE and colistin-resistant Enterobacteriales in pregnant women during labour. Carbapenem and colistin-resistant Enterobacterales can cause the following infections: bacteraemia; nosocomial pneumonia; urinary tract infections, and intra-abdominal infections. Due to limited treatment options, infections caused by these multidrug-resistant organisms are associated with a mortality rate of 40-50%. Screening for colonisation of carbapenem-resistant Enterobacteriaceae (CRE) and colistin-resistant Enterobacteriaceae will help implement infection and prevention measures to limit the spread of these multidrug-resistant organisms.

2022-07-20 | GSE208573 | GEO

Animal and human sharing of mcr-1-positive Enterobacterales, Portugal

Project description:mcr-1 sharing between co-habiting dogs and humans in the community, Portugal 2018-2020

| PRJEB45751 | ENA

CREST-E dbGaP Data Sharing

Project description:CREST-E dbGaP Data Sharing

| PRJNA419024 | ENA

CREST-E dbGaP Data Sharing

Project description:CREST-E dbGaP Data Sharing

| PRJNA419023 | ENA

Project description:Clinical carbapenemase/AmpC-producing Enterobacterales isolates

| PRJNA763348 | ENA

LC-MS/MS analysis demonstrates a decrease in porins and increase in CMY-2-like beta-lactamases in E. coli exposed to meropenem

Project description:While ESBL and AmpC beta-lactamases barely degrade carbapenems, they are able to bind them and prevent them from interacting with penicillin binding proteins thereby preventing their effect. When these beta-lactamases are expressed at a high level and combined with a decreased influx of carbapenems due to a decrease in membrane permeability, Enterobacterales can become resistant to carbapenems. In this study we developed a LC-MS/MS assay for the detection of the E. coli porins OmpC and OmpF, it’s chromosomal AmpC beta-lactamase and the plasmid-mediated CMY-2 beta-lactamase. Subsequently, we cultured CMY-2 positive E. coli isolates in the presence of meropenem and analyzed mutants that showed increased resistance to meropenem using our developed assay and western blot. In all five selected strains, a decrease in OmpC and/or OmpF was the first event towards an increase in meropenem minimum inhibitory concentrations (MICs). Subsequently, in four of the five isolate series, MICs increased further after an increase in CMY-2-like production.

2022-04-04 | PXD025363 | Pride

Escherichia coli strain:Z2_24

Project description:Fecal AMR Enterobacterales in Companion Animals

| PRJNA1280510 | ENA

Inducible AmpC β-lactamases detected in Southeast Asian Escherichia coli and Klebsiella pneumoniae isolates

Project description:AmpC β-lactamases in SE Asian Enterobacterales

| PRJEB76280 | ENA

Enterobacterales

Project description:Enterobacterales colonisation of hospital sink drains

| PRJNA604910 | ENA