Project description:Iridovirus is an important viral pathogen affecting large yellow croaker. Megalocytivirus FD2018 with a spanning genome of 112,214 bp double-stranded DNA with a G + C content of 53.53% and 130 predicted genes with ORF sizes of 41 to 1293 amino acids, these virion proteins are predicted to be involved in virion assembly, DNA replication, transcription, nucleotide metabolism and protein modification. Proteomic analysis identified 55 proteins in the cell culture supernatants and purified viral particles.
Project description:Aedes aegypti mosquitoes infect hundreds of millions of people each year with dangerous viral pathogens including dengue, yellow fever, Zika, and chikungunya. Progress in understanding the biology of this insect, and developing tools to fight it, depends on the availablity of a high-quality genome assembly. Here we use DNA proximity ligaton (Hi-C) and Pacific Biosciences long reads to create AaegL5 - a highly contiguous A. aegypti reference.
