Project description:Geographical location influences the composition of the gut microbiota in wild house mice (Mus musculus domesticus) at a fine spatial scale
Project description:Purpose: Identify genes disregulated in wild type C57Bl6 mouse lung tissue in the house dust mite (HDM) asthma disease model and genes differentially expressed in ALOX15 KO mice.
Project description:We employed RNA-sequencing to identify differentially expressed genes between two wild-derived inbred mouse strains. These strains exhibit high collateral blood vessel densities, but differ in widely in infarct volume following middle artery occlusion. This experiment helped facilitate identification of candidate loci underlying this differential response.