Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Whole-genome sequencing of novel Burkholderia cepacia complex species: Burkholderia mycopellens and Burkholderia crassaminum

ABSTRACT: Whole-genome sequencing of novel Burkholderia cepacia complex species

PROVIDER: PRJEB76175 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other
	ERR13696561_1.fastq.gz	Fastqsanger.gz
	ERR13696561_2.fastq.gz	Fastqsanger.gz
	ERR13696562_1.fastq.gz	Fastqsanger.gz
	ERR13696562_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 16

Similar Datasets

Burkholderia cepacia complex

Project description:Sequencing of multiple species of the Burkholderia cepacia complex

| PRJNA525973 | ENA

Burkholderia cepacia

Project description:Novel Burkholderia cepacia outbreak in the US

| PRJNA297031 | ENA

Burkholderia species

Project description:Novel Burkholderia cepacia complex species-Genome sequencing and assembly

| PRJNA391085 | ENA

Expression data from Burkholderia cepacia IST408 bceE and bceF mutants

Project description:The bacterial tyrosine (BY) kinase family comprises the major group of bacterial enzymes endowed with tyrosine kinase activity. We have previously shown that the BceF protein from Burkholderia cepacia IST408 belongs to this BY kinase family and is involved in the biosynthesis of the exopolysaccharide cepacian. However, little is known about the extent of regulation in the cell by this kinase protein. In order to examine this, we performed a comparative transcriptome profile between the bceF mutant and the wild-type B. cepacia IST408. As a control, the transcriptome of another exopolysaccharide-deficient mutant, which had a mutation in the bceE gene, was also determined.

2012-12-01 | GSE38183 | GEO

An investigation of Burkholderia cepacia complex methylomes via SMRT sequencing and mutant analysis

Project description:While nucleotide sequences determine an organism’s proteins, methylation of the nucleotides themselves can confer additional properties. In bacteria, differences in methylation can be used to identify incoming DNA, for example from bacteriophages. Restriction enzymes detect the methylation status at specific sequence motifs, and cleave improperly methylated, foreign DNA. Furthermore, methylation of key genetic regions can influence gene expression and hence phenotype. In this study, we determined the methylated motifs of three strains from the closely-related Burkholderia cepacia complex of opportunistic pathogens. Three of these motifs were novel, while two are methylated throughout this group of bacteria and beyond and had already been assigned putative causative genes. To investigate the contribution of the enzymes that methylate and cut DNA, we deleted the genes encoding them from a representative strain. We found that these genes are important for traits including motility, biofilm formation, cell shape and production of iron acquisition elements. The mutant strain showed marked defects in replicon partitioning and was more efficient at acquiring foreign DNA, illustrating the importance of methylation in maintaining genome integrity. Interestingly, we found that one methylase, part of an integrated bacteriophage genome, was essential for maintaining the phage in a dormant state.

2021-06-01 | GSE147038 | GEO

Burkholderia cepacia

Project description:Burkholderia cepacia Genome sequencing

| PRJNA1183809 | ENA

Burkholderia cepacia

Project description:Burkholderia cepacia Genome sequencing

| PRJNA785711 | ENA

Burkholderia cepacia

Project description:Burkholderia cepacia Genome sequencing

| PRJNA863394 | ENA

Burkholderia cepacia

Project description:Burkholderia cepacia Transcriptome or Gene expression