Project description:In this experiment, we used four diets, one based on FM, a challenging diet with 40% soybean meal (SBM), and two diets containing 40% SBM with 5% of Cyberlindnera jadinii yeast exposed to different down-stream processing conditions (heat-inactivated or autolysation). The immunomodulatory effects of the diets were analyzed in the spleen of Atlantic salmon after 37 days of feeding. The results showed that the inclusion of autolysed C. jadinii (ACJ) was able to modulate the response of Atlantic salmon compared to fish fed the SBM-diet, through the activation of biological pathways related to endocytosis, PPRs-signal transduction and transporter activity. Finally, we suggest that the spleen is a good candidate to characterize the immunomodulatory effects of functional ingredients in Atlantic salmon.
Project description:This is genome-scale metabolic model of Cyberlindnera americana as the representative yeast species for the clade Phaffomycetaceae. This model was generated through homology search using a fungal pan-GEM largely based on Yeast8 for Saccharomyces cerevisiae, in addition to manual curation. This model has been produced by the Yeast-Species-GEMs project from Sysbio (www.sysbio.se). This is model version 1.0.0 accompanying the publication (DOI: 10.15252/msb.202110427), currently hosted on BioModels Database and identified by MODEL2109130008. Further curations of this model will be tracked in the GitHub repository: https://github.com/SysBioChalmers/Yeast-Species-GEMs Models for species of the same clade includes: Cyberlindnera fabianii; Cyberlindnera jadinii; Wickerhamomyces anomalus; Wickerhamomyces ciferrii; Starmera quercuum; Candida stellimalicola; Candida freyschussii; Cyberlindnera mrakii; Cyberlindnera misumaiensis; Candida montana; Barnettozyma californica; Barnettozyma hawaiiensis; Barnettozyma populi; Barnettozyma pratensis; Barnettozyma salicaria; Candida ponderosae; Wickerhamomyces hampshirensis; Wickerhamomyces bovis; Wickerhamomyces alni; Wickerhamomyces sp.; Cyberlindnera petersonii; Wickerhamomyces canadensis; Starmera amethionina; Phaffomyces opuntiae; Phaffomyces antillensis; Phaffomyces thermotolerans; Candida orba; Cyberlindnera saturnus; Cyberlindnera suaveolens; Cyberlindnera xylosilytica; Candida mycetangii; Candida vartiovaarae; Cyberlindnera maclurae; Cyberlindnera americana. These models are available in the zip file. To cite BioModels, please use: V Chelliah et al; BioModels: ten-year anniversary. Nucleic Acids Res 2015; 43 (D1): D542-D548. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to MIT License for more information.
2021-11-01 | MODEL2109130008 | BioModels
Project description:WGS data of wild Cyberlindnera jadinii strains
