Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Bulk transcriptomic profiles of mouse testes in response to male environmental exposures across age and genetic background

ABSTRACT: Bulk transcriptomic profiles of mouse testes in response to male environmental exposures across age and genetic background

PROVIDER: PRJEB82786 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR13994427_1.fastq.gz	Fastqsanger.gz
	ERR13994427_2.fastq.gz	Fastqsanger.gz
	ERR13994428_1.fastq.gz	Fastqsanger.gz
	ERR13994428_2.fastq.gz	Fastqsanger.gz
	ERR13994429_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 62

Similar Datasets

Bulk transcriptomic profiles of mouse testes in response to male environmental exposures in the young FVB background

Project description:Bulk transcriptomic profiles of mouse testes in response to male environmental exposures in the young FVB background

| PRJEB82785 | ENA

Small RNA profiles of mouse sperm in response to male environmental exposures across age and genetic background

Project description:Small RNA profiles of mouse sperm in response to male environmental exposures across age and genetic background

| PRJEB82753 | ENA

Bulk transcriptomic profiles of mouse testes in response to male environmental exposures across age and genetic background

Project description:This study includes raw data of testis RNA-seq profiles from treated (nABX & LPHS, with nABX: non-absorbable antibiotics and LPHS: low-protein, high sugar diet) and control (CON) males of mature (57-62 weeks) and young (9-11 weeks) FVB & C57BL/6J backgrounds. Sequencing was done using 40bp paired-end reads on a NextSeq500 sequencer, obtaining an average of 25 million reads per sample.

2024-11-22 | E-MTAB-14638 | biostudies-arrayexpress

Bulk transcriptomic profiles of mouse testes in response to male environmental exposures in the young FVB background

Project description:This study includes raw data of testis RNA-seq profiles from treated (nABX & LPHS, with nABX: non-absorbable antibiotics LPHS: low-protein, high sugar diet) and control (CON) males of young (10-11 weeks) FVB background. Sequencing was done using 40bp paired-end reads on a NextSeq500 sequencer, obtaining an average of 25 million reads per sample.

2024-11-22 | E-MTAB-14637 | biostudies-arrayexpress

Small RNA profiles of mouse sperm in response to male environmental exposures across age and genetic background

Project description:This study includes raw data of sperm smallRNA profiles from treated (nABX & LPHS, with nABX: non-absorbable antibiotics ; LPHS: low-protein, high sugar diet) and control (CON) males across FVB and C57BL/6J genetic backgrounds and mature (76-78 weeks (>1yr)) and young (10-11 weeks) ages. Sequencing was conducted at 100 bp, single-end on a Nextseq2000, resulting in approximately 1-5 million reads for most samples.

2024-11-22 | E-MTAB-14636 | biostudies-arrayexpress

Single-embryo transcriptomic profiles of mouse blastocysts in response to paternal environmental exposures in young FVB background

Project description:Single-embryo transcriptomic profiles of mouse blastocysts in response to paternal environmental exposures in young FVB background

| PRJEB82789 | ENA

Single-embryo transcriptomic profiles of mouse blastocysts in response to paternal environmental exposures in young C57BL/6J background

Project description:Single-embryo transcriptomic profiles of mouse blastocysts in response to paternal environmental exposures in young C57BL/6J background

| PRJEB82790 | ENA

Drosophila Testis Proteome - Stage-specific testes proteomics of Drosophila melanogaster identifies essential proteins for male fertility

Project description:Spermiogenesis in Drosophila melanogaster is a highly conserved process and essential for male fertility. In this haploid phase of spermatogenesis, motile sperm are assembled from round cells, flagella are assembled, and needle-shaped nuclei with highly compacted genomes are formed. We aimed at identifying proteins relevant for the maturation phase from spermatids to sperm. As transcription takes place mainly in spermatocytes, and transcripts with relevance for post-meiotic sperm development are translationally repressed for days, we comparatively analysed the prote-ome of larval testes (stages before meiotic divisions), of testes of 1–2-day-old pupae (meiotic and early spermatid stages) and adult flies (late spermatids and sperm). We identified 6677 pro-teins, with 422 solely detected in larval testes, 623 in pupal testes and 634 in adult testes. We analysed a few so far uncharacterized proteins with repect to stage specific expression and im-portance for male fertility. For example, Mst84B (gene CG1988), a very basic cysteine- and lysine-rich nuclear protein, was present in the phase of transition from a histone-based to a pro-tamine-based chromatin structure. CG6332 encodes d-Theg, which is related to the mouse tHEG and human THEG proteins. Mutants of d-Theg lacked sperm in the seminal vesicles and were sterile. The identification of numerous predicted proteins underscores the high potential of pro-teome analysis for future analyses of spermatogenesis.

2019-02-01 | PXD010627 | Pride

Novel imprint control regions (ICRS) responsive to environmental exposures

Project description:Novel imprint control regions (ICRS) responsive to environmental exposures

| PRJNA863714 | ENA

Halothane/Isoflurane repetitive exposures

Project description:Halothane/Isoflurane repetitive exposures

| PRJNA99515 | ENA