Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Freshwater metagenomics study of Pune City, India

ABSTRACT: Freshwater metagenomics study of Pune City, India

PROVIDER: PRJEB83103 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Monkeypox virus: Genome sequencing by MCL, ICMR-NIV PUNE, ICMR-NIV, PASHAN-PUNE

Project description:Monkeypox virus: Genome sequencing by MCL, ICMR-NIV PUNE, ICMR-NIV, PASHAN-PUNE, Pune, India

| PRJEB106259 | ENA

An RNA signature for tuberculosis risk in pregnant women: a prospective cohort study from Pune, India

Project description:An RNA signature for tuberculosis risk in pregnant women: a prospective cohort study from Pune, India

| PRJNA707605 | ENA

OSCC CGH SriLanka vs India

Project description:In Asia, oral cancer (OC) and oral submucous fibrosis (OSF) constitute major health problems linked to use of betel quid. This work performed CGH genome-wide analysis of OC (12 from India, 12 from Sri Lanka) and OSF (6 from India) cases with normal controls.

2011-11-30 | E-MTAB-819 | biostudies-arrayexpress

Metagenomics study

Project description:Metagenomics study

| PRJEB38060 | ENA

Hydra vulgaris strain:Ind-Pune

Project description:Hydra vulgaris strain:Ind-Pune Epigenomics

| PRJNA532677 | ENA

metagenomics study

Project description:metagenomics study about microbial diversity

| PRJEB12719 | ENA

Hydra vulgaris strain:Ind-Pune

Project description:Hydra vulgaris strain:Ind-Pune Transcriptome or Gene expression

| PRJNA451264 | ENA

metagenomics NGS study

Project description:metagenomics NGS study

| PRJEB42456 | ENA

An RNA signature for tuberculosis risk in pregnant women: a prospective cohort study from Pune, India

Project description:Background: Pregnant and postpartum women are at high risk of developing active tuberculosis (TB), but transcriptional TB studies have excluded pregnant women. We identified differentially expressed genes (DEGs) in pregnant women who did and did not progress to active TB. Methods: We followed a cohort of pregnant Indian women with TB infection for one year postpartum, collecting blood at study entry, 6 weeks postpartum and active TB diagnosis. A prospective signature of risk was identified by comparing whole blood RNA sequencing data from women who developed active TB postpartum (cases) with those who remained healthy (controls). Results: We identified 9 cases and matched them to 18 controls by HIV status and gestational age. A gene set of risk was identified: Expression of KCNIP4 > 2.2 log CPM and S1PR4 < 7.3 log CPM indicated a high probability of developing active TB postpartum. SF3B4 (>4.3 log CPM) and PGAM1 (>6.6 log CPM) correctly classified postpartum cases and controls. Both pairs displayed high accuracy (AUC >0.9) and were unique from 36 published TB signatures.Conclusions: We identified two genes that prospectively differentiated pregnant women who developed active TB postpartum from those who did not. If validated, this signature could be useful in targeted TB prevention programs.

2021-09-01 | GSE168519 | GEO