Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Evolution experiment tub2T238A

ABSTRACT: Evolution experiment tub2T238A

PROVIDER: PRJEB83891 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR14103600_1.fastq.gz	Fastqsanger.gz
	ERR14103600_2.fastq.gz	Fastqsanger.gz
	ERR14103601_1.fastq.gz	Fastqsanger.gz
	ERR14103601_2.fastq.gz	Fastqsanger.gz
	ERR14103602_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 108

Similar Datasets

Beta-lactam evolution experiment H. influenzae Rd KW20

Project description:Evolution experiment H. influenzae Rd KW20

| PRJEB86018 | ENA

Evolution experiment tub2T238A

Project description:Laboratory evolution experiments of yeast cells impaired for microtubule dynamics. The sequencing was done at two time-points, early and late, to identify compensatory mutations. For details see Macaluso et al, Cell Reports, 2025.

2025-01-08 | E-MTAB-14739 | biostudies-arrayexpress

Evolution of gene expression during long term coexistence in a bacterial evolution experiment

Project description:We used microarrays to study the evolution of gene expression in two bacterial ecotypes that coexisted for more than 35000 generations of experimental evolution in an extremely simple environment We sampled four clones from each of two lineages at generations 6,500, 17,000 and 40,000 from the polymorphic Ara-2 population of the E. coli long-term evolution experiment. The four clones from each lineage and generation were mixed equally and used for global expression profiling, growth assays and competition experiments. Global expression profiles and growth assays were also performed on the ancestral strain. RNA extractions were done using cells in mid-exponential growth in the same glucose-limited minimal medium used in the evolution experiment. Global expression profiles were obtained by using Affymetrix arrays, with 5 or 6 biological replicates for each lineage-generation sample.

2012-01-01 | E-GEOD-30639 | biostudies-arrayexpress

Evolution of gene expression during long term coexistence in a bacterial evolution experiment

2012-01-01 | GSE30639 | GEO

Evolution of gene expression in one population of the Long-Term Evolution Experiment with Escherichia coli

Project description:Evolution of gene expression in one population of the Long-Term Evolution Experiment with Escherichia coli

| PRJNA522618 | ENA

Analyzing the process of mutation accumulation in KRAS evolution experiment using amplicon sequencing

Project description:Directed evolution in mammalian cells can facilitate the engineering of mammalian-compatible biomolecules and can enable synthetic evolvability for mammalian cells. We engineered an orthogonal alphaviral RNA replication system to evolve synthetic RNA-based devices, enabling RNA replicase-assisted continuous evolution (REPLACE) in live mammalian cells. Using REPLACE, we attempted continuous intracellular evolution of the negative dominant mutant KRAS (S17N). To analyze the process of mutation accumulation, we performed amplicon sequencing on experimental materials at different stages and under different treatment conditions. The results indicated that the mutations generated by this system were primarily induced by Monanunavir, and the addition of Monanunavir significantly accelerated the rate of evolution.

2024-07-07 | GSE235327 | GEO

Evolution of gene expression in one population of the Long-Term Evolution Experiment with Escherichia coli

Project description:We used microarrays to study the changes in whole-genome expression profiles accompanying the evolution of one bacterial population propagated in glucose minimal medium for 20,000 generations.

2019-04-16 | GSE126600 | GEO

Analyzing the process of mutation accumulation in KRAS evolution experiment using amplicon sequencing

Project description:Analyzing the process of mutation accumulation in KRAS evolution experiment using amplicon sequencing

| PRJNA985699 | ENA

Analyzing the process of mutation accumulation in MEK1 evolution experiment using amplicon sequencing

Project description:Analyzing the process of mutation accumulation in MEK1 evolution experiment using amplicon sequencing

| PRJNA985697 | ENA

Immigration Experiment

Project description:Immigration Experiment

| PRJEB75447 | ENA