Project description:Probing the texture of the rare biosphere: We have bracketed the dimensions of the rare biosphere in two marine bacterial samples by comparing a deep (1 million sequences per sample) pyrosequencing analysis of the two samples and the cultures isolated from one of them.

| PRJEB9061 | ENA

Deep Biosphere - Beatrix 326 BH2 (270712)

Project description:This project aims to investigate the metabolic pathways expressed by the active microbial community occurring at the deep continental subsurface. Subsurface chemoLithoautotrophic Microbial Ecosystems (SLiMEs) under oligotrophic conditions are supported by H2; however, the overall ecological trophic structures of these communities are poorly understood. Some deep, fluid-filled fractures in the Witwatersrand Basin, South Africa appear to support inverted trophic pyramids wherein methanogens contributing <5% of the total DNA apparently produce CH4 that supports the rest of the community. Here we show the active metabolic relationships of one such trophic structure by combining metatranscriptomic assemblies, metaproteomic and stable isotopic data, and thermodynamic modeling. Four autotrophic β-proteobacteria genera that are capable of oxidizing sulfur by denitrification dominate. They co-occur with sulfate reducers, anaerobic methane oxidizers and methanogens, which each comprises <5% of the total community. Defining trophic levels of microbial chemolithoautotrophs by the number of transfers from the initial abiotic H2-driven CO2 fixation, we propose a top-down cascade influence of the metabolic consumers that enhances the fitness of the metabolic producers to explain the inverted biomass pyramid of a multitrophic SLiME. Symbiotic partnerships are pivotal in the deep biosphere on and potentially beyond the Earth.

2018-10-27 | PXD004634 | Pride

Andean uncovered biosphere

Project description:Andean uncovered biosphere: revealing the vertical miliscale bacterial and eukaryotic community structure and relationships within a microbial mat from Salar de Huasco

| PRJEB26321 | ENA

Million Veteran Program (MVP) Summary Results from Omics Studies

Project description:Million Veteran Program (MVP) Summary Results from Omics Studies

| PRJNA486224 | ENA

Million Veteran Program (MVP) Summary Results from Omics Studies

Project description:Million Veteran Program (MVP) Summary Results from Omics Studies

| PRJNA486225 | ENA

Deciphering cis-regulatory logic with 100 million synthetic promoters

Project description:Deciphering cis-regulatory logic with 100 million synthetic promoters

| PRJNA414104 | ENA

Raw read archive of EPIGEM

Project description:This archive contains raw reads produced by the Epidemiology and Genomics unit at the Laboratoire National de Santé, mainly on isolates of foodborne pathogens

| PRJEB11695 | ENA

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